Main Presenter: Dr. Stijn Meganck

• Vrije Universiteit Brussel, Belgium
• Pleinlaan 2, 1050 Brussels, Belgium
• Email address: smeganck@vub.ac.be
• Tel: +32 2 629 37 11 Fax: +32 2 629 37 08
• Home page URL: http://como.vub.ac.be/doku.php?id=members:stijn_meganck 
• Teaching experience:
    o Teaching Assistant: Adaptive Systems, Logic, Artificial Intelligence
    o Lecturer KdG College: Mathematics, Java Programming, Computer Networks
• Earlier tutorial presentations:
    o Subgroup Discovery in Bioinformatics, Guest lecture at King Mongkut’s University of Technology Thonburi, Thailand, 2009.
    o Probabilistic Graphical Models: Guest lecture at King Mongkut’s University of Technology Thonburi, Thailand, 2006.
    o From Probabilistic to Causal Graphical Models: Seminar, University of Hasselt, Belgium, 2004.
    o Causal Discovery in Non-Ideal Frameworks: Seminar, MICRAC, France, 2009.

Second Presenter: Mr. Jonatan Taminau

• Vrije Universiteit Brussel, Belgium
• Pleinlaan 2, 1050 Brussels, Belgium
• Email address: jtaminau@vub.ac.be
• Tel: +32 2 629 37 06 Fax: +32 2 629 37 08
• Home page URL: http://como.vub.ac.be/doku.php?id=members:jonatan_taminau
• Teaching experience:
    o Teaching Assistant: Project 3rd year Bachelor
• Earlier tutorial presentations:
    o None

Abstract:

Introductory level

There is a massive amount of freely available genomics data on the web and very powerful analysis tools exist as well. However, biologists and researchers spend a large amount of their time filtering and cleaning data before it can be analyzed. Furthermore, results of studies are often non-reproducable.

The InSilico project was started with the intention of overcoming these problems. We present the approaches taken in our project as well as a demonstration of the InSilico DB.

Requirements: An introductory knowledge of general bio-informatics, specially suited for those working with expression data.

If internet is available for participants, then participants can connect to the InSilico DB with their laptop and follow the demonstration in real time.

Tutorial Outline:

• Total time: 2 hours including 10 min break
• Introduction (15 mins)
    o Situation of the project
    o Related approaches
    o Open problems
• Data (15 mins)
    o Annotation
    o Quality
• Merging (15 mins)
    o Situation of the problem
    o State-of-the-art algorithms
    o Open problems
• Large-scale genomics (15 mins)
    o Applications
    o Future prospects
• 10 min break
• Demonstration + Tutorial of InSilico DB (35 mins)
• Questions and Answers (15 mins)